Factorial Assignment

Factorial assignment is a type of clinical study in which groups of participants receive one of several combinations of interventions. For example, two-by-two factorial assignment involves four groups of participants. Each group receives one of the following pairs of interventions: (1) medicine A and medicine B, (2) medicine A and a placebo, (3) a placebo and medicine B, or (4) a placebo and a placebo. Therefore, during the clinical study, the different groups of participants receive all possible combinations of the two medicines (A and B) and the placebos. (CTG)